Empirical Cycling Community Notes

Watts Doc 5: Can You Lift Heavy While Endurance Training?

Original episode & show notes | Raw transcript

Introduction: The Athlete’s Dilemma

For endurance athletes, particularly cyclists, the question of whether to incorporate heavy strength training is a long-standing debate with two main camps:

  1. The “Off-Season Only” Camp: This traditional periodization view argues that strength training is not specific to the primary sport. Therefore, it should be confined to the off-season and base-building phases and eliminated as the competitive season approaches to maximize sport-specific fitness.

  2. The “Year-Round Maintenance” Camp: This school of thought posits that the strength and power built in the off-season are valuable assets that will diminish if not maintained. Since cycling, even sprinting, involves relatively low force compared to maximal lifting, proponents argue for year-round lifting to preserve these gains.

Understanding the science behind how our bodies adapt to these different stimuli is key to navigating this dilemma and making the best choice for your athletic goals.

Why Should Endurance Athletes Lift? The Neural Advantage

While benefits like increased bone density are crucial for athletes in low-impact sports like cycling, the most immediate and significant gains from strength training are neural.

The Interference Effect: A Scientific Discovery

The core issue with combining strength and endurance training is a phenomenon known as the interference effect.

The Hickson (1980) Study: A Landmark Experiment

This was one of the first studies to systematically investigate concurrent training (doing both strength and endurance training simultaneously).

The Molecular Basis of Interference: mTOR vs. PGC-1α

Modern science has revealed the molecular pathways that explain Hickson’s findings. Adaptation is a battle for resources within the cell, governed by competing signaling pathways.

mTOR: The “Build Muscle” Pathway

PGC-1α: The “Build Endurance” Pathway

The Molecular Conflict

The critical discovery is that the PGC-1α pathway (along with a related energy-sensing protein, AMPK) actively inhibits the mTOR pathway.

When you perform endurance exercise, you trigger a strong PGC-1α signal. This signal essentially tells the cell, “Prioritize aerobic adaptation and energy efficiency now; shut down the resource-intensive process of building new muscle.” Because the aerobic signal takes evolutionary precedence, it can override the muscle-building signal.

Practical Applications: Manipulating the Interference Effect

Understanding these pathways allows you to structure your training to achieve your desired outcome.

1. Training Order and Timing Matter Because the PGC-1α signal is short-lived (3 hours) while the mTOR signal is long-lived (18+ hours), you can manipulate the timing of your workouts.

2. Mind Your Fiber Types Muscle fibers are plastic and adapt to the stimulus you provide.

3. Use Nutrition as a Tool You can stimulate the mTOR pathway without lifting.

4. Periodize Your Goals